2′-Deoxyadenosine CAS 958-09-8 Purity ≥99.0% (HPLC) UV Assay ≥98.0% High Purity
Manufacturer Supply Deoxynucleosides Intermediates with High Purity and Stable Quality
| 2'-Deoxyguanosine monohydrate CAS: 961-07-9 | 2'-Deoxyadenosine CAS: 958-09-8 |
| 2'-Deoxyuridine CAS: 951-78-0 | 2'-Deoxycytidine CAS: 951-77-9 |
| 5-Iodo-2'-Deoxyuridine CAS: 54-42-2 |
| Chemical Name | 2'-Deoxyadenosine |
| Synonyms | 2'-Deoxyadenosine Anhydrous |
| CAS Number | 958-09-8 |
| CAT Number | RF-PI204 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C10H13N5O3 |
| Molecular Weight | 251.25 |
| Melting Point | 187.0~189.0℃ |
| Water Solubility | Soluble in Water |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White or Off-White Crystalline Powder |
| Solution Clarity Test | Clear |
| UV Spectrum (pH 7) | A250 / A260 = 0.76~0.82 A280 / A260 = 0.13~0.17 |
| Water Content (K.F) | ≤8.0% |
| Residue on Ignition | ≤0.50% |
| Heavy Metals | ≤20ppm |
| Arsenic | ≤2ppm |
| UV Assay | ≥98.0% (on dry basis) |
| Purity | ≥99.0% (HPLC) |
| Test Standard | Enterprise Standard |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
2'-Deoxyadenosine (CAS: 958-09-8), also called DNA nucleoside A, is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA. 2'-Deoxyadenosine is a kind of natural deoxyribose nucleoside, is the structure of the DNA fragments, and other natural nucleoside involved in almost all living cells in the transfer of genetic information, affecting the synthesis of protein and polysaccharide of metabolism, and the organism, such as cell growth, proliferation, differentiation, and inhibiting plays an important regulatory role. It is not only an important raw material for gene medicine and gene engineering research, but also has a good physiological activity. 2'-Deoxyadenosine can inhibit insulin release induced by sugar, and can reduce the effect of specific phosphodilipase inhibitors or adenosine cyclase activator to promote insulin secretion.
In addition, 2'-Deoxyadenosine (CAS: 958-09-8) can also be used as an important intermediate of antiviral, anticancer and anti-AIDS drugs. For example, 2' -fluoro-2 '-deoxyadenosine and Clatribine (2' -chloro-2 '-deoxyadenosine) have excellent anti-tumor effects. Dideoxyadenosine (ddA) has a high activity against HIV and HBV, and acyclovir has a strong inhibitory effect on HSV-1 and HSV-2 viruses. These are important drugs that are widely used internationally.
